Large International Projects

 

   Large International Projects COORDINATED by DSV in the past 10 years

 

  1. TRIM-NET (2019 - 2022)
  2. ROC-POP-LIFE (2017 - 2020)
  3. MEMORY-net (2017 - 2019)
  4. CSMON Life (2014 - 2017)
  5. ANASTOMOSEAL (2012 - 2017)
  6. Trans2Care (2011 - 2014)
  7. InnovH2O (2011 - 2014)
  8. SiiT (2011 - 2013)
  9. KeyToNature (2007 - 2010)

 

  Large International Projects with DSV as PARTNER in the past 10 years

 

  1. VIVALDI (2016 - 2020)
  2. ATeNA (2014 - 2020)
  3. AdriAquaNet (2014 - 2020)
  4. PreCanMed (2014 - 2020)
  5. No Waste (2014 -2020)
  6. Agrotur II (2014 - 2020)
  7. POS FESR - NATIinFVG (2014 - 2020)
  8. POS FESR - BioApp (2014 - 2020)
  9. POS FESR - oraCle (2014 - 2020)
  10. Graphene Flagship (2013 - 2020)
  11. FocusINCD (2016 - 2019)
  12. Agrotur (2011 - 2014)
  13. Biodinet (2007 - 2013)
  14. GEP (2011 - 2013)
  15. 3Corala (2007 - 2013)
  16. PESCA (2007 - 2013)
  17. NEWBONE (2006 - 2010)
  18. NANOBIOPHARMACEUTICS (2006 - 2010)

 


2019-2022, LEAD PARTNER

 “TRIM-NET: Training network in drug discovery targeting TRIM ubiquitin ligases in disease” is a project funded by the European Union Horizon 2020 MSCA-IT programme.

TRIM-NET is a 4-year Marie Sklodowska-Curie Innovative Training Network project funded with a total budget of 3,2 M€. It aims at addressing TRIM ubiquitin ligase activity and regulation to develop novel therapeutics for the treatment of different types of cancer, rare genetic neuromuscular disorders, and neurodegenerative diseases.

The project is coordinated by Germana Meroni of the Department of Life Sciences, University of Trieste and includes 9 academic partners from the United Kingdom, Spain, Germany, France, Germany and Netherlands, plus 5 non-academic Partner Organisations. The TRIM-NET consortium is designed to bring together a multidisciplinary team, which connects different expertise (genetics, biochemistry, molecular and cell biology, chemical biology, structural biology) across Europe.

Marie Skłodowska-Curie ITN actions aim to promote training and international mobility for early stage researchers; the TRIM-NET consortium will recruit 12 young researchers in the different Nations involved in the project.

For info: gmeroni@units.it or trimnet@units.it

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2017-2019, LEAD PARTNER

MEMORI-net - Mental and Motor Rehabilitation Network of stroke is a cross-border Italy-Slovenia project, that aims to delineate new common clinical standardised protocols for the rehabilitation of stroke patients with a new Diagnostic, Therapeutic and Care Strategy. In particular, the project will implement the criteria for the evaluation of the deficit in stroke patients and will design new integrated cognitive and motor rehabilitation strategies. An ICT platform will facilitate the cooperation between institutions, stakeholders, and families, also with dedicated training initiatives.


With more than 1 million new cases/year incidence, stroke represents one of the most urgent causes of cognitive and motor disability in European countries. Stroke might occur in young productive adults, and therefore it has a profound impact on the health system, families, and the whole local economy. Even if the stroke is an acute vascular lesion in the brain, it can provoke disability in the entire body, thus requiring multidisciplinary rehabilitation practices, that are not always accessible in the territory. Rehabilitation of patients after stroke involves, therefore, different institutions and requires a strong coordination between stroke centres and rehabilitation units. The management of stroke patients in a cross-border region, furthermore, needs also technologies and instruments to facilitate communication and integration of linguistic minorities, with strategies to overcome legal limitations related to the transfer of personal medical information across the border.
MEMORI-net is a joined effort to ameliorate the management of post-stroke rehabilitation, in order to define common diagnostic and therapeutic protocols based on the most advanced scientific knowledge and the best international practices. With more than 4000 new stroke cases per year in the cross-border Programme Area, stroke is one of the most urgent causes of intellectual and motor disability.
MEMORI-net integrates excellence in the territory related to stroke management and e-health, with the coordination of specialized clinical Stroke Units, University centres leader in diagnostic biomarkers and IC technologies, rehabilitation centres, Terme and locally active stroke patient's associations.
With a strong education and training programme targeted to medical doctors, caregivers and families, MEMORI-net, therefore, favours the exchange of knowledge and the amelioration of rehabilitation practices offered to the patients of Italy and Slovenia.

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PDF icon Brochure di MEMORY-net

 


2017 - 2020, LEAD PARTNER

This project is a concrete conservation action aiming to restore in two marine Natura2000 sites (that are Specially Protected Areas of Mediterranean Importance - ASPIM) the Habitat 1170, by reintroducing Cystoseira . According to the Habitat Directive (92/43/EEC), all the species of the genus Cystoseira are Habitat of Community Interest by the EU (Habitat Reef - code 1170 Annex I of the Habitats Directive ECD 92/43/EEC) and the different species are used for the definition of the NATURA2000 Habitat1170 on the Mediterranean coasts (Italian Interpretation Manual of the 92/43/EEC Directive Habitat). Moreover the target Cystoseira are priority in Habitat 1170 for ASPIM sites.

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2014 - 2020

NATIinFVG: NIPT per Aneuploidie Tracciabili e Informatizzate nel Friuli Venezia Giulia

Description

 


2014-2017, LEAD PARTNER

 

Un approccio di Citizen Science al monitoraggio della biodiversità per la soluzione delle problematiche ambientali.

 

 
CSMON-LIFE (Citizen Science MONitoring) is one of the first Italian projects which focuses on using a citizen science approach on biodiversity. I was funded by the European Commission under the LIFE+ programme. The project want to stimulate the participation of the citizens, involving them in the study, management and conservation of biodiversity, hence creating an active collaboration between citizens, scientific community and institutions. The project targets individuals, schools and several categories (hikers, fishermen, farmers, boaters, divers, etc.).

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2012-2015, LEAD PARTNER

 

Development of a resorbable sealing patch for the prevention of anastomotic leakage after colorectal cancer surgical treatment.

 

 

The AnastomoSEAL Consortium is working to develop a new product to prevent the anastomotic leakage: a biocompatible, resorbable sealant patch which is applied around the site of anastomosis, and promotes healing of the site as well as acting as a physical barrier to help prevent leakage. (EU – NMP –FP7)

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2011-2014,  LEAD PARTNER

Transregional Network for Innovation and Technology Transfer to Improve Health Care
Rete transregionale per l'innovazione ed il trasferimento tecnologico per il miglioramento della sanità
Tansregionalno omrežje za inovacijo in prenos tehnološkega znanja za izboljšanje zdravstva


 

Trans2Care was a project aimed at creating a trans-regional network for innovation and technology transfer in the health system, active between 2011 and 2014, as part of the Cross-border Cooperation Programme Italy-Slovenia 2007-2013 . Coordinated by the Department of Life Sciences, Trans2Care involved 13 Partners, equally distributed in Italy (north-east) and Slovenia.

To promote innovation in the healthcare systems, Trans2Care brought together experts in medicine, technology and business, and hired 14 post-doc researchers to translate research results into innovative applications for the diagnosis and treatment of common diseases. These researchers have been actively involved in a complementary technology and entrepreneurial training program, which has opened up job opportunities in the R & D sector for at least 2 years after the end of the project.

The Trans2Care project is considered by the European Commission a good practice to reduce brain drain.

Reference person: Dr. Sabina Passamonti

 

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Trans2Care Books

 


 

2011-2014,  LEAD PARTNER

 

Innov-H2O was a project aimed at creating a cross-border network for innovation and technology transfer in aquaculture, active between 2011 and 2014, as part of the Cross-border Cooperation Programme Italy-Slovenia 2007-2013. Coordinated by the Department of Life Sciences, Innov-H20 involved 8 Partners, equally distributed in Italy (north-east) and Slovenia.

Innov-H20 brought together biology and veterinary researchers, mediators between research and producers and 2 companies. Thanks to an intense mediation activity (focus groups, thematic tables, meetings), the researchers have directed their studies towards the problems represented by the producers and these now have technical-scientific references at the universities and research centers.

Reference person: Dr. Sabina Passamonti

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2011-2013,  LEAD PARTNER

 

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2007-2010,  LEAD PARTNER

 

 

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2016 - 2020

VIVALDI: Preventing and Mitigating Farmed Bivalve Diseases

 

VIVALDI (Preventing and Mitigating Farmed Bivalve Diseases) is a European scientific project, financed in the framework of the EU Research and Development programme called Horizon 2020. It is carried out by a consortium of 21 partners, from 10 countries. It will last 4 years, till February 2020. VIVALDI’s overarching purpose is to increase the sustainability and competitiveness of the European shellfish industry. For this, it will aim at improving the understanding of the diseases and developing practical solutions to prevent, control and manage them. The main species to be studied will be: oysters, mussels, clams and scallops. 

 

Reference person: prof. Alberto Pallavicini

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PDF icon Vivaldi brochure


 

2014 - 2020

ATeNA: Technological Applications of New Antineoplastic

 

In the last two decades the possibility of altering the functionality of the ubiquitin-proteasome system (UPS) has aroused much interest in oncology research and for the drug development strategies of Biotech companies. The UPS is a system dedicated to protein degradation; the neoplastic cells are very dependent on it because, accumulating mutations, they produce altered proteins that must be rapidly degraded. Inhibition of UPS, through the induction of a proteotoxic stress, results in the death of neoplastic cells. Bortezomib and carfilzomib are two first-generation UPS inhibitors, used clinically for the treatment of multiple myeloma and mantle cell lymphoma. These inhibitors, although having not shown benefits in the treatment of solid tumors, have stimulated the interest of companies and research groups to identify new UPS inhibitors. The global R&D market for UPS in 2013 was estimated at 2.9 billion dollars with a forecast for 2018 of 5.5 billion. The ATeNA project aims, in a multidisciplinary perspective, to evaluate the therapeutic potential of a new lead compound, 2cPE, capable of inhibiting the UPS and inducing proteotoxic stress. 2cPE is an inhibitor of isopeptidases, enzymes components of UPS. ATeNA will focus on ovarian cancer studies, which represent 5% of neoplasms and a challenge that is still unresolved for both diagnosis and treatment. Surgical removal associated with systemic chemotherapy does not achieve good results and the prognosis is often poor. In this context, new therapeutic approaches based both on the use of new molecules and innovative delivery tools are urgently required. A further need is also to have effective and rapid tools for evaluating therapeutic benefits. The multidisciplinary nature of ATeNA guarantees an integrated and innovative approach by supplying the antineoplastic associated with its effectiveness markers. The UNIUD beneficiary, in collaboration with the UNITS beneficiary, identified the isopeptidase inhibitor and the same was suitably modified as a pro-drug for in vivo use. Early pre-clinical studies in animal models have shown low toxicity and confirmed the anti-neoplastic action. With ATeNA it will be possible to generate more powerful versions of 2cPE, improve delivery, characterize mechanisms of action, identify prognostic markers to better target in vivo studies and initiate an evaluation of the efficacy of 2cPEon ovarian cancer, directly using the cells of the patients.

 

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2014 - 2020

AdriAquaNet - Enhancing Innovation and Sustainability in Adriatic Aquaculture

The AdriAquaNet project, Enhancing Innovation and Sustainability in Adriatic Aquaculture, funded by the EU Interreg V Italy-Croatia Program 2014-2020, is led by a group of researchers from the University of Udine and links seven other research institutions, including the University of Trieste, four companies and a Cluster, operating both in Italy and in Croatia. This community, which has about 100 experts, will work for two and a half years in the first ever technical-scientific cooperation initiative, with the aim of transferring advanced knowledge and new technologies to the aquaculture supply chain, from the management of the plants to production up to the market of processed products.

The University of Trieste, represented by prof. Sabina Passamonti and Alberto Pallavicini of the Department of Life Sciences, participates in all organizational levels of the project, from the direction of a work plan that includes as many as 20 lines of activity to the external communication of the results of the project. Furthermore, researchers from our University will carry out biochemical and genetic research to measure the health of farmed fish, exploiting some specific biological similarities between these marine vertebrates and humans. Their results will contribute to the characterization of the food quality of the farmed fish and support the principle that farmed fish is important for our health.

Details

Priority: Blue Innovation
Duration: 01.01.2019-30.06.2021
Coordination: University of Udine, Italy
Grant: € 2.740.408 from the European Regional Development Fund and € 483.601 from national co-funding nazionale

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Contacts: Dr. Sabina Passamonti 

 


2014-2020

 

BioApp project envisages to establish sustainable flow of information among stakeholders included in the production of products made out of innovative biopolymer material with high added value. In addition, BioApp aims at development of services focused on the needs of the food, cosmetics and health related industries in the Programme area, in order to increase the level of competitiveness and stimulate economic growth for new employment opportunities.

 

Project Brochure

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2014-2020

oraCle: New integrated approach to oral therapy of Crohn’s disease

 

 

Project description

 


2013 - 2020

Graphene Flagship

Started in 2013, the Graphene Flagship is a Future and Emerging Technology Flagship established by the European Commission. The main goal of the flagship consists in bringing together academic and industrial researchers to take graphene from the realm of academic laboratories into European society in a timeframe of 10 years. The Department of Life Sciences together with the Department of Chemical and Pharmaceutical Sciences, University of Trieste is involved in the “Work Package 4 -Health and Environment”, leaded by Prof. M. Prato. This Work Package takes care of nanosafety of graphene-based materials at different levels, i.e. towards humans, plant organisms and the environment, as an essential requirement that cannot be separated from the development of new nanotechnologies.

 

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2011-2014

The Agrotur project was an Italian-Slovenian cooperation project to improve the quality of Terrano del Carso wine. It involved 4 scientific partners and 2 producer consortia, active between 2011 and 2014, as part of the Cross-border Cooperation Programme Italy-Slovenia 2007-2013. Lead by the Agricultural Institute of Slovenia, it has carried out studies on the quality of the environment, wine and the biological properties of the bioactive substances contained in it. It has created a hotel network for tourism enhancement of the territory and its products.

Reference person: Dr. Sabina Passamonti

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2011-2013

 

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2007-2013

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2007-2013

 

 

 

Web page progetto

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2007-2013

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2006-2010

 

Development of load-bearing fibre reinforced composite based non-metallic biomimetic bone implant

The major aim of NEWBONE project was to develop Fibre and Nanohybrid reinforced composite (FRC and NHRC) material for surgical bone repair and replacement where load-bearing and ligament fixation capabilities are essential. NEWBONE project has developed FRC and NHRC material for surgical bone repair and replacement where load-bearing and ligament fixation capabilities are essential. (EU – NMP –FP6)

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2006-2010

 

Nanoscale Functionalities for Targeted Drug Delivery of Biopharmaceutics.

 

 

The project aimed at the development of innovative multidisciplinary approaches for the design, synthesis and evaluation of functionalized nanocarriers and nanoparticle-based microcarriers for the treatment of various diseases based on targeted, controlled delivery of therapeutic peptides and proteins (biopharmaceutics). (EU – NMP –FP6)

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  2014 - 2020

 

The PreCanMed project aims to strengthen the collaboration between Italian and Austrian institutions that perform genetic, clinical and biotechnology research in order to establish a common competence-platform for the generation, cultivation and storage of patient-derived tumor-organoids, a promising tool for future precision cancer medicine. Know-how on this technology will be made accessible to the academic, translational, clinical and pharmaceutical research and development sector.

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2014 - 2020

Project description

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Certottica

Kompetenzzentrum Holz

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2014 - 2020

The AGROTUR II project - Sustainable development of agriculture and tourism in the cross-border Karst stregthens cross-border collaboration to increase the scientific knowledge and technologies needed to improve the quality of DOC Terrano wine, reduce the environmental impact of viticulture and promote local tourism . Six partners share technical-scientific objectives and competences. The project is coordinated by the Agricultural Institute of Slovenia. Other Partners are the Universities of Nova Gorica and Udine, the Municipality of Komen (Slovenia) and the Confesercenti of Venice.

Reference person: Dr. Sabina Passamonti

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Project in action

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Last update: 07-18-2019 - 11:45