Il giorno lunedì 20 maggio p.v. alle ore 16:00 presso l'aula Z dell'edificio G, piazzale Europa si terrà il seminario intitolato "ENVIRONMENTAL AND DIETARY FACTORS IN NEUROPSYCHIATRIC DISORDERS: FOCUS ON THE GUT-BRAIN AXIS"

Il seminario è organizzato dalla scuola di specializzazione in Farmacologia e Tossicologia Clinica e dal dottorato in Medicina Personalizzata e Terapie Innovative.

Abstract dell'evento

ENVIRONMENTAL AND DIETARY FACTORS IN NEUROPSYCHIATRIC DISORDERS: FOCUS ON THE GUT-BRAIN AXIS

The “fil rouge” between metabolic alterations and neuropsychiatric disorders has become more relevant in public health. Indeed, obesity and mood disorders share several pathogenic mechanisms in both the central nervous system and the periphery. The microbiota-gut-brain axis is a bidirectional network conveying signals influencing gut and brain functions. Indeed, peripheral pro-inflammatory cytokines triggered by dysmetabolism reach the hypothalamus, the main regulator of food intake, triggering microglial and astrocytic activation and the following neuroinflammation. The onset of these deleterious events affects other connected brain areas, such as the mesolimbic system which regulates motivation and reward, inducing mood alterations. The investigation of risk factors, such as environmental stressors, and the discovery of new pharmacological/nutritional approaches are necessary for disentangling the intricate network between the gut and the brain.

Date e orari

20 maggio 2024 alle ore 16:00

Luogo

Aula Z dell'edificio G, Comprensorio di piazzale Europa.