Cellular and Molecular Neuropathology (Dr. Cesca)

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Dr. Fabrizia Cesca

Tel.: +39 040 558 8727

Email: fcesca@units.it

 

Biosketch

Dr. Fabrizia Cesca holds a tenure-track researcher position in neurophysiology at the University of Trieste, Department of Life Sciences, since December 2018, and is affiliated to the Center for Synaptic Neuroscience and Technology of the Istituto Italiano di Tecnologia (Genova).

Fabrizia graduated with honours in Biological Sciences at the University of Padova in 2003, and subsequently conducted her doctorate studies at the University College of London (UCL), working at the Cancer Research UK Institute, in Prof. G. Schiavo’s laboratory, until 2008. She continued her research experience at the Istituto Italiano di Tecnologia (IIT) in Genova, in the Neuroscience and Neurotechnologies Department led by Prof. Benfenati, first as a post-doc and then as a researcher, until she moved to Trieste.

Fabrizia’s main scientific interest concerns the cellular and molecular mechanisms that control the development and survival of neural cells (neurons, astrocytes), in particular for what concerns the response to neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF). Over the years Fabrizia has studied the physio-pathological role of the neuronal protein Kidins220/ARMS, employing both in vitro cultures of primary neuronal cells, and in vivo analysis of full and conditional knockout transgenic mouse lines. Overall, these studies have identified Kidins220 as a crucial component of the intracellular signaling pathways initiated by neurotrophins, with an important role in neuronal differentiation and in the modulation of network plasticity. More recently, Fabrizia has been part of the European ‘GRAPHENE’ Flagship: within this context, Fabrizia contributed to characterize the physiological impact of carbon nanomaterial exposure to primary neurons and astrocytes.

Fabrizia teaches the Neuropathology course (glial neuropathology module) of the International Master in Neuroscience, and the Neurophysiology course of the Bachelor’s Degree in Psychological Sciences and Techniques.

Fabrizia authored 32 publications on international peer-reviewed journals, 2 book chapters and a number of other scientific publications. She collaborates with the Edi Ermes publishing group to prepare a textbook about ‘Elements of Human Physiology’. Moreover, Fabrizia is actively engaged in dissemination activities, including seminars and lectures addressing high school students (Amici del Festival della Scienza, Genova) or the general public (Caffè delle Scienze, Trieste).

 

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Last update: 03-30-2020 - 21:30